According to today's epidemiological bulletin, a new daily maximum of new cases was reached, with a further 3,960 infections, surpassing the 3,669 new cases registered on 24 October.
Portugal has already reported 128,392 new coronavirus infections and 2,395 deaths.
Of the 24 deaths registered in the last 24 hours, 11 occurred in the Northern region, eight in Lisbon and the Tagus Valley, four in the Centre and one in Alentejo.
The number of people admitted to hospital has continued to rise for more than a week, with 1,794 people now hospitalised, 47 more than on Tuesday, and of these 262 (nine more) are in intensive care units.
The DGS reveals that 51,996 cases of infection are active, 2,279 more than on Tuesday.
Also in the last 24 hours, 1,657 people have been recovered, exceeding the 74,000 (74,001) barrier since the beginning of the pandemic.
Health authorities now have 62,457 people under surveillance, 2,394 more in the last 24 hours.
The northern region continues to register the highest number of new infections every day, with 2,114 more cases today, totalling 56,122, and 1,053 dead, 11 of them in the last 24 hours.
In the Lisbon and Tagus Valley region a further 1,105 new cases of infection have been reported, with the region accounting for 55,478 cases and 995 deaths, eight of which in the last 24 hours.
In the Centro region there were 558 new cases, accounting for 10,877 since the beginning of the pandemic and 304 deaths.
In Alentejo a further 110 cases of infection were registered, totalling 2,558 with a total of 43 deaths since the beginning of the pandemic.
The Algarve region has today reported 53 more cases of infection, totalling 2,579 cases and 25 deaths.
In the Autonomous Region of the Azores five more cases have been registered in the last 24 hours, totalling 353 detected infections and 15 dead since the beginning of the pandemic.
Madeira has registered 15 new cases in the last 24 hours, accounting for 425 infections, with no record of deaths to date.
The confirmed cases are spread over all age groups, with the highest number of infections recorded between 20 and 59 years.
In total, the new coronavirus has already affected at least 58,374 men and 70,018 women in Portugal, according to the reported cases.
Of the total number of deaths, 1,224 were men and 1,171 women.
The highest number of deaths continues to be concentrated in people over 80 years of age.
The Covid-19 pandemic has already caused more than 1.1 million deaths and more than 44 million cases of infection worldwide, according to a review by the French agency AFP.
The disease is transmitted by a new coronavirus detected at the end of December 2019 in Wuhan, a city in central China.