The data released today show that the number of new cases has more than doubled in the last 24 hours from 249 to 646.
Since the beginning of the pandemic, Portugal has already registered 1,849 deaths and 61,541 cases of infection, says the DGS daily report on the epidemiological situation of Covid-19 in the country.
Of the three deaths, two were recorded in the Lisbon and Tagus Valley region and one in the Northern region.
35,151 contacts remain under surveillance, 685 more than on Tuesday.
In the Lisbon and Tagus Valley region 290 new cases have been reported, accounting for 31,563 and 689 deaths since the beginning of the pandemic.
The northern region now has a further 276 cases, with a total of 22,325 deaths.
In the Centre region, 40 more cases were observed in the last 24 hours, totalling 5,044 infections and 254 deaths, according to data from the Directorate General for Health.
The Alentejo region registered another 23 infections by SARS-Cov-2, the coronavirus that causes covid-19 disease, now totalling 1,021 cases and 22 deaths.
According to the data, the Algarve region now has 15 more cases, totalling 1,186 infections and 17 deaths since the beginning of the pandemic.
The Autonomous Region of the Azores has reported another case, making a total of 228 infections and 15 deaths.
Madeira also registered a new case today, accounting for 174 Covid-19 infections and no deaths.
The DGS also reports that 138 patients have recovered in the last 24 hours, totalling 43,284 recovered people since the beginning of the pandemic in Portugal.
The number of inpatients has dropped to 391 (minus three) and the number of patients in intensive care units has risen to 52 (plus two).
Confirmed cases are spread over all age groups, with the highest number of infections recorded between 20 and 59 years of age.
In total, the new coronavirus affected at least 27,744 men and 33,797 women in Portugal, according to the reported cases.
Of the total number of deaths, 930 were men and 919 women.
The highest number of deaths continues to be concentrated in people over 80 years of age.
The Covid-19 pandemic has already claimed at least 898,503 lives and infected more than 27.6 million people in 196 countries and territories, according to a report by the French agency AFP.
The disease is transmitted by a new coronavirus detected at the end of December in Wuhan, a city in central China.
After Europe succeeded China as the centre of the pandemic in February, the American continent now has the most confirmed cases and the most deaths.