"We regret to inform you that Madonna is unable to perform this evening due to pain from her ongoing injuries,” reads a post put up on Wednesday on the Facebook page of the promotor, Everything is New. “Therefore the Madame X concert scheduled for tonight, January 22, at The Lisbon Coliseum is cancelled.

“The final Lisbon show tomorrow, Thursday, January 23rd is expected to go on as scheduled,” the statement adds.

Madonna had already cancelled Sunday’s planned concert, citing her need to rest. At the time, a post in the singer's Instagram account apologised for the cancellation, signing off with an "until Tuesday".

According to Everything is New, refunds of tickets for Wednesday's concert " should be requested at the outlet where the ticket was bought from 24th January at 1pm.” People who bought their tickets online “will be notified by e-mail,” it adds in the Facebook post.

The ‘Madame X’ tour arrived in Europe on 12 January, with a total of 37 concerts in Lisbon, London and Paris scheduled until the end of March. It had already crisscrossed the US, where there were initial production problems and cancellations towards the end due to an injury suffered by the singer.

As well as a young Portuguese musician who plays the Portuguese guitar in the show, Gaspar Varela, great-grandson of the late Celeste Rodrigues - a fado singer of whom Madonna was an admirer - the tour also features Portuguese trumpet player Jessica Pina, percussionists Carlos Mil-Momens and Miroca Paris, and the Cabo Verde all-female group Batukadeiras.

Madonna has said that both the new album and this tour draw on creative influences from the singer’s experience living in Lisbon for several years recently, during which she came into contact with Portuguese-language and southern European culture.

Made with the collaboration of French producer Mirwais, the album ‘Madame X’ features collaborations with Brazilian singer Anitta and Colombian musician Maluma.

The ‘Madame X’ concerts, which are staged in smaller and more intimate venues that have been usual for Madonna in earlier years, include some new songs, such as "God Control" and "I Rise", but also older material such as "Express Yourself", which she has performed a capella, "American Life" and "Papa don't preach".

Madonna first performed in Portugal in 2004, closing her ‘Re-Invention’ tour in Lisbon. The following year she performed in Lisbon at the MTV European Music Awards ceremony.

She returned in 2008 and in 2012 performed in Coimbra.