Carla Vanessa (4th minute), Fifó (7th) and Rute Duarte (10th) scored the goals for Portugal. Patricia González (3rd), Consu (16th) and Mayte Mateo (29th and 34th) scored the goals for Spain.
On Wednesday, the two teams faced each other again, also in Tenerife.
Portugal and Spain could meet in the final stage of the Euro, which is to take place in Gondomar, northern Portugal, between 15 and 17 February, if they win in the semi-finals and against Ukraine and Russia, respectively.