Carriço, a central defender who plays for Seville, and Sanches, a midfielder who plays for Lille, have been called up before, while for Olympiacos striker Podence it is his first time.
In contrast to the finals of the League of Nations tournament, national manager Fernando Santos has left out forward Dyego Sousa, who plays for Shenzhen, in China.
Juventus striker Cristiano Ronaldo remains the biggest star in the team, who won the inaugural League of Nations and are also reigning European champions. They are now seeking their first win in the qualifying round for the 2020 championships.
So far Portugal have drawn twice at home, against Ukraine (0-0) and Serbia (1-1).
Portugal are currently fourth in group B with only two points, although they have played two fewer matches than Ukraine, who lead with 10 points, and Luxembourg, who are second with four.
Serbia, who have played one more game than Portugal, are third in the table, also with four points, while Lithuania are last, with one point.