The deaths in the last 24 hours occurred in the North region.
According to the DGS bulletin, 332 patients are now hospitalised in infirmary, 14 less than on Tuesday, and 88 in intensive care units, two more.
Since the beginning of the pandemic Portugal has recorded 835,563 confirmed cases and 16,973 deaths.
The number of hospitalisations both on the ward and in intensive care units have values close to those recorded in September 2020.
Regarding the number of new cases, today's figures are similar to those recorded in recent weeks, with daily fluctuations.
There are 23,809 active cases in Portugal, seven less than on Tuesday and the number of contacts under surveillance by health authorities has also decreased by 299, now totalling 24,712.
The data also reveals that 576 people have been reported recovered, bringing the total number since the start of the pandemic in Portugal in March 2020 to 794,781.
According to the latest DGS data, Portugal currently has 3,012,175 people vaccinated against Covid-19, of which 806,991 are already immunised with both doses.
The transmissibility index (Rt) of the SARS-Cov-2 coronavirus in Portugal rose today to 1, while the incidence of infection cases per 100,000 inhabitants in the last 14 days dropped to 69.3 according to data released today.
The previous figures for these indicators, released on Monday, showed a Rt of 0.99 and an incidence of 70.4 cases per 100,000 inhabitants.
Rt and incidence data are updated on Mondays, Wednesdays and Fridays.
In the Lisbon and Tagus Valley region, 186 new infections have been reported, with 316,065 cases and 7,193 deaths counted so far.
The North region has 261 new infections by SARS-CoV-2 and since the beginning of the pandemic has counted 335,648 cases of infection and 5,340 deaths.
These two regions now account for 78.1 percent of the total number of new infections.
In the Centre region, 61 more cases were registered, accumulating 118,582 infections and 3,014 deaths.
In Alentejo two more cases were reported, totalling 29,756 infections and 970 deaths since the beginning of the pandemic.
In the Algarve region, today's bulletin reveals that 31 new cases have been registered, accumulating 21,619 infections and 357 deaths.
The Autonomous Region of Madeira has registered nine cases, accounting for 9,170 infections and 68 deaths due to Covid-19 since March 2020.
The Azores now has 22 new cases and counts 4,723 cases and 31 deaths since the start of the pandemic, according to the DGS.
The regional authorities of the Azores and Madeira release their data daily, which may not coincide with the information released in the DGS bulletin.
The new coronavirus has already infected at least 379,066 men and 456,187 women in Portugal, DGS data show, according to which there are 310 cases of unknown gender, which are under investigation as this information is not provided automatically.
Of the total number of fatalities, 8,914 were men and 8,059 women.
The highest number of deaths continues to be concentrated in the elderly over 80 years old, followed by the age group between 70 and 79 years old.
Of the total deaths, 11,169 were people aged over 80, 3,614 were aged between 70 and 79, and 1,519 were aged between 60 and 69.
The pandemic caused at least 3,137,725 deaths worldwide, resulting from more than 148.6 million cases of infection, according to a report by the French agency AFP.