The route between the city in the north of Portugal and the northwest of France will be guaranteed through three weekly frequencies, on Mondays, Wednesdays and Fridays.
With more than 17,000 available seats, this link will be operated from December this year.
In addition to this route, easyJet will offer nine other new connections between cities in its European network.
José Lopes, General Director of easyJet for Portugal, said: “It is with great enthusiasm that we present yet another new route from Portugal. The connection between Porto and Rennes will start operating this winter and, similarly to what we did in the summer months, will allow our customers to travel more easily, whether for work or leisure.
“This new route reinforces once again easyJet's commitment to our country and our desire to offer passengers an increasingly varied offer.
In addition, we are also very happy to present nine more connections in our European network, thus being able to satisfy the needs and respond to the demand of those who intend to travel this Christmas and in the other winter months.”