Thirty pieces of art ranging from the 19th century to the present are part of the Irish News Collection.
A portrait of Sir William Orpen's daughter Christine, also known as Kit, is one of the highlights. Estimated to be worth between £70,000 and £105,000, Kit's portrait was drawn in 1912, when the little subject was just six years old.
Fitzpatrick, who passed away last year at the age of 92, spent forty years amassing his art collection.
Prominent Irish painters include Frank McKelvey, John Behan, Harry Kernoff, Margaret Clarke, Gerard Dillon, and Basil Blackshaw are among those whose works are included.
One of the oldest and most prestigious fine art auctioneers in the world, Bonhams, will put the works up for sale in a special Dublin event.
“Proud to announce its first sale on the island of Ireland,” the firm declared.
From November 24 to November 28, the Irish News Collection will be on display in Dublin's City Assembly House, with an online sale and live bidding.
Offering “an exciting and rich selection of works” is something that Bonhams said it was glad to be doing.
Since it is believed that the Fitzpatricks personally own the art collection, the transaction is a private issue, and as such, The Irish News was unable to comment on its last night.
The newspaper relocated to the Fountain Centre earlier this year after selling Ulster University its historic Donegall Street headquarters in Belfast.
“The sale of the historic Irish News building to Ulster University creates a fantastic legacy for what was the home of our newspaper for over a century,” stated Dominic Fitzpatrick, managing director of Irish News.
“We are excited about all the opportunities associated with our new home, but we will be sad to leave Donegall Street, which has served us so well over the generations.”
It was revealed earlier this month that the Fitzpatrick family had sold the Fountain Centre to Michael Herbert, the former KFC magnate.
For an unknown amount, the businessperson and developer successfully acquired the office and retain building located in the middle of Belfast city.
Q Radio is owned by the Fitzpatrick family, who also control the Irish News.
Following his father's passing in June of last year, Dominic Fitzpatrick paid homage, saying, "Dad was an inspiration to so many people." He oversaw the transformation of the publication into the current success.
He quietly but efficiently worked in the background for the majority of his life, contributing to the efforts to bring about peace in Ireland.
“He worked in the community, always attempting to unite people and advance society. Up until a few weeks ago, he continued to come into the office because he enjoyed what he did.
“Every day, he said a morning prayer that essentially encapsulated his outlook on life.”
Born in Belfast, Mr. Fitzpatrick attended a boarding school in Limerick and then a university in Galway to pursue his legal studies.